The park has wetland forest with Mahogany and fig trees, open land, savannah, marshes and acacia woodland. There are large numbers of wild animals such as common zebras, herds of buffaloes and elephants, giraffes, impala, waterbuck, bushbuck, wildebeest, klipspringer, spotted hyena and leopard.
Lake Manyara is noted for its wealth of birdlife from the birds of prey to the water birds. Also resident are flocks of flamingoes, pelicans, ostriches, marabou storks, white-backed ducks and goliath heron. In the lake there are of hippos.